GRIBOI Keynote Speakers

Douglas Beall


Title of the talk: Basivertebral Nerve Ablation: Diagnostic and Therapeutic Challenges

Marc Bohner

RMS Foundation, Bettlach, Switzerland

Title of the talk: Does a temporal drop of extracellular calcium level induce heterotopic ossification in injured tissues?

Dr. Marc Bohner holds a MSc and PhD degree from the Swiss Federal Institute of Technology of Lausanne (1990, 1993). His career included positions as postdoctoral fellow at the University of Utah, and the Swiss Federal Institute of Technology of Zurich. In 1998, he joined RMS Foundation, a private research and testing lab located in Bettlach, Switzerland. Currently, he serves as a research director and leads the “Bioceramic & Biocompatibility Group”. His interests include the synthesis, production, and use of calcium phosphates for bone repair.

He holds over fifteen distinct patents, is the inventor of 4 commercial products, and has published and presented widely in his field (≈130 articles; h = 50-60). He has given 140 invited lectures in English, French, and German. His teaching positions have included adjunct and affiliated appointments at the University of Sherbrooke (2004 – 2019), the University of Berne (2011 – present), and ETH Zurich (2009 – present).

His services to the scientific community include: Editor of Acta Biomaterialia (2008 à; IF = 10.6); Co-chair of the annual congress of the European Society for Biomaterials (2009); Secretary, vice-president and president of the Swiss Society for Biomaterials (2004 – 2012); Secretary and president of “GRIBOI” (2007 – 2016); Secretary and then treasurer of the European Society for Biomaterials (2013 – 2021); Member of the Research Council of the Swiss National Science Foundation (2016 – present). In 2013, he received a “honorary life membership” from the Swiss Society for Biomaterials. In 2014, he was awarded the “Racquel LeGeros Award” of the “International Society for Ceramics in Medicine” for his contribution to calcium phosphate research. In 2016, he became “honorary president” of GRIBOI.

Allan Brook


Title of the talk: Treatment of Vertebral Osteoporotic Compression Fractures : cement vs real bone augmentation

Jiang Chang


Title of the talk: Develpment of injectable bioactive composites for tissue repair

Professor Jiang Chang, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Fellow of International Union of Societies for Biomaterials Science and Engineering (FBSE), Fellow of Royal Society of Chemistry (FRSC), and Fellow of American Institute of Medical and Biological Engineering (AIMBE). Ph.D in 1991 in Chemistry from the Technical University of Darmstadt in Germany. Post Doctoral Research Fellow at the Medical University of Luebeck in Germany (1991-1993); Research fellow at the School of Medicine, University of Auckland in New Zealand (1993-1997); Research Assistant Professor in the Medical School at New York University (1997-1999); Research scientist at Johnson&Johnson USA(1999-2000); Professor and founder of the Biomaterials and Tissue Engineering Research Center of the Shanghai Institute of Ceramics. Professor Chang is a vice president of the Interdisciplinary Research Society for Bone and Joint Injectable Biomaterials (GRIBOI). His research focuses on bioactive materials including bioceramics and composites for tissue regeneration and tissue engineering. Professor Chang has over 500 scientific papers published in international peer-reviewed scientific journals (with more than 29000 citations and H-index 94) and 70 patents.

Oliver Clerk

Founder & President, Beam Radiology, ASNR – Spine Interventional Council, Canada

Title of the talk: Treatment of Painful Lumbar Degenerative Disc Disease: Canadian Experience

  • Chief Medical Officer and Founder of Beam Radiology, Calgary, Canada
  • Neuroradiologist and musculoskeletal interventionalist. Expert in diagnosing spine pathologies and performing image guided interventional treatments.
  • Board certified in Diagnostic Radiology by the Royal College of Physicians and Surgeons of Canada and Interventional Pain Management by the World Institute of Pain (Fellow of Interventional Pain Practice)
  • Associate member of McCaig Institute for Bone and Joint Health in Calgary
  • Inaugural member of the Interventional Spine Council of the American Society of Neuroradiology (ASNR)
  • Interventional Pain Management Committee Leader of the Society of Interventional Radiology (SIR)

Christèle Combes


Title of the talk: The calcium carbonate – calcium phosphate system as a toolbox for injectable and customized bone cements

Christèle Combes received her PhD in Materials Science at the Institut National Polytechnique de Toulouse (INPT, France) in 1996. In 1997, she held a postdoctoral position at the Ecole Polytechnique de Montréal (Canada) dedicated to the development of polysaccharide based hydrogels for cartilage substitution and repair. Since 1998, she has been a teacher-researcher at the Ecole Nationale Supérieure des Ingénieurs en Arts Chimiques et Technologiques (ENSIACET) in Toulouse. Currently professor, head of the Materials Science and Engineering Department of ENSIACET-INP Toulouse, she has been at the head of the ‘‘Phosphates, Pharmacotechnics, Biomaterials’’ research group of the CIRIMAT laboratory from 2007 to 2015. Her research focuses on calcium phosphate and calcium carbonate based biomaterials and biomineralizations in a view to substitute and/or repair bone defects and to go towards better understanding the formation of normal and pathological calcifications. She is the treasurer of the GRIBOI association since 2010 and in the scientific committee of the International Society for Ceramics in Medicine since 2014. Professor Christèle Combes has over 100 scientific papers published in international peer-reviewed scientific journals and 8 patents.

Stephen Ferguson

ETH Zurich, Institute for Biomechanics, Zurich, Switzerland

Title of the talk: Prophylactic Augmentation: Biomechanical Potential and Pitfalls

Stephen Ferguson is a full professor of biomechanics at the ETH Zurich, with over 30 years’ experience in orthopaedic research. The focus of his research is the study of the mechanical and biological mechanisms of musculoskeletal disorders and injuries and the use of innovative biomaterials and technologies for their treatment. His group employs experimental, computational and biological methods, from the cell scale to the whole body.

Dimitrios K Filippiadis

Diagnostic and Interventional Radiology at the Medical School of National and Kapodistrian University of Athens, Greece

Title of the talk: Advanced image guided navigation for spine interventions

  • Associate Professor of Diagnostic and Interventional Radiology at the Medical School of National and Kapodistrian University of Athens.
  • Over 130 scientific publications, hundreds of scientific and business presentations, 32 book chapters, and substantial industrial grant support.
  • CIRSE Fellow and the recipient of more than 15 major honors/awards.
  • Has served in the scientific program committees of CIRSE, SIO, ECR, RSNA and in the Editorial Board of major journals including CVIR. Currently, serves as Chairperson of CIRSE Online Education Committee

Joshua Hirsch


Title of the talk: A Neiman Fellow on health policy considerations in device development

Jack Jennings


Title of the talk: Ablation and cement augmentation for the treatment of painful osseous metastatic lesions.

Alexis Kelekis


Ulrike Kettenberger


Title of the talk: Combining systemic and local osteoporosis treatments: first results in rodents.

Ulrike Kettenberger holds a MSc in Mechanical Engineering from the Technical University of Munich (TUM) and a PhD in Bioengineering from the Swiss Federal Institute of Technology Lausanne (EPFL). She  is co-founder and CTO of flowbone SA, a young EPFL-spinoff that develops an injectable biomaterial for the regeneration of diseased bone. She discovered the core technology underlying the flowbone product while doing her PhD thesis at the Laboratory of Biomechanical Orthopedics (LBO) at EPFL.

Gianluca Maestretti

HFR Fribourg-HĂ´pital Cantonal, Freiburg, Switzerland

Title of the talk:
1. Posterior approach VC fractures why and when.
2. Titanium trabecular 3D EBM implants to promote bone stimulation and ingrowing: from bench to bedside.

Prof. Tit. Clin. Maestretti is an Orthopedic trained surgeon from the HĂ´pital Cantonal Fribourg University Hospital Fribourg in Switzerland.

He joined the HFR back in in 2002 as head of the spinal unit of the department of orthopedics and since 2017 as chief physician of the HFR site and co-head of the department.

The HFR’s neurospinal unit has been recognized as a subspecialty training center in spine surgery since 2022.

In addition Professor Maestretti is part of many society, scientific’s groups, collaborates as a reviewer of articles for ESPJ and collaborates with several companies in the development of implants and holder of several patents.

Expertise about but not limited to:

Traumatology spine surgery; degenerative surgery; adult deformity surgery; prosthetic surgery; minimally invasive surgery; infection; tumor surgery and revision surgery.

Luigi Manfrè

Minimal Invasive Spine Therapy dept – Mediterranean Institute for Oncology I.O.M., Catania, Italy

Title of the talk: Microinstability – who to treat and how to treat.

Stefano Marcia


Title of the talk: New Musculosekeletal devices used in Europe, not yet available in America

Dr. Stefano Marcia was born in Cagliari on 12/07/1965.

After high school, he received his graduate degree in medicine and surgery from Cagliari University in 1990 and his board in Radiology in 1995 from the same University. He also received the master in endovascular techniques (advanced) from the University of Rome in 2005, the master in management of health companies from Luiss Business school of Rome in 2011 and the master in health management from University of Sassari in 2023.

Dr. Marcia is currently is the chief of Radiology at SS. TrinitĂ  Hospital in Cagliari, Italy.

His primary field is spine interventional radiology and he personally performed treatments for trauma (vertebral fractures), degenerative diseases (disk, facet joint, spinal canal) and tumor ablation; in particular he has been involved in development of new device for the treatment of spinal canal stenosis.

He trained in Cagliari University and he organizes annually the MAMMI hands-on spine course for training in spine procedures; he also trained many physicians as private consultant for several companies.

He has published 37 papers and he has 8 book contributions; he had delivered 81 lectures or scientific papers as first author.  He has reviewed articles for Cardiovascular Interventional Radiology (CVIR), European Journal of Radiology (EJR), Journal of Vascular And Interventional Radiology (JVIR), Neuroradiology,

Journal of Bone Oncology and BMC Musculoskeletal Disorders; he is part of BMC Musculoskeletal Disorders and CVIR Editorial board.

Kieran Murphy


Management of Tarlov cysts an uncommon but serious life-altering spinal column disease – What do we know now through evidence and experience with over 1,000 patients?

Professor Kieran Murphy MB BAO BCH FRCPC FSIR graduated in 1986 from the Royal College of Surgeons in Ireland. He completed his Radiology residency and Neuroradiology fellowship at the University of Michigan, and Interventional Neuroradiology fellowship at University of Geneva. From 1998-2008 he was Division Head of Interventional Neuroradiology at Johns Hopkins. Since 2008 he has been Prof of Radiology at University of Toronto. He holds 81 patents including vertebroplasty systems, bone cements, biopsy systems, and other medical devices to treat spine, neurovascular and CSF pathologies. H-Index 44. Citations 7515.

Malin Nilsson


Title of the talk: Disc augmentation with PMMA bone cement with and without cement softener – pre-clinical and clinical review

Diego San Milan


Title of the talk: Percutaneous management of vertebral metastasis with extreme osteolyis

Silvia Santiago

Spain Title of the talk: Third-generation percutaneous vertebral augmentation system

Sean Tutton


Title of the talk: Third-generation percutaneous vertebral augmentation system

Dr. Tutton is a Professor of Radiology and Orthopedics at UCSD Health.

Dr. Tutton received his degree from Rutgers University, New Jersey School Medical School in 1991 and completed his internship, residency and fellowship at the Feinberg School of Medicine, Northwestern University in Chicago IL.  He spent 16 years at the Medical College of Wisconsin serving as Chief of VIR and Vice Chair and most recently joined UCSD in 2021.  

His clinical focus has been caring for cancer and non-cancer patients with pain and advancing the art of interventional radiology through clinical research. He received additional board certification in Hospice and Palliative Care in 2012. His principal areas of interest include treatment of musculoskeletal tumors with embolization, ablation, and stabilization of pathologic fractures.

He helped develop a minimally invasive treatment of patients suffering from painful cancer related pelvic fractures utilizing a combination of ablation, screw, and cement fixation which interventionalists are now utilizing at multiple centers around the world.

Stefan Weber

Professor Weber is CEO of CASCINATION AG and Professor for Image-guided Therapies, at the ARTORG Center of the University of Bern, Switzerland. Between 2011 and 2019 he was Director of the ARTORG Centre for Bioengineering Research. His research and commercial focus is on image-guided systems for surgical robotics and interventional guidance procedures for ENT, Hepatobiliary and Neurology reach from basic investigative research to CE/FDA approved devices sold and used in clin-ics worldwide. His technologies include CAS-One IR™ an image guidance system for percutaneous tumour ablation in liver cancer and the HEARO™ ENT Robotic technology for use in Cochlear Implantation. Through novel ways of embedding his team into the clinical workflow environment, Prof Weber has introduced disruptive technology and surgical approaches into clinics, effecting a paradigm shift from open surgery to image- and sensor guided interventions. His academic endeavours are the mindful exploration of biomedical engineering at the interface of technology and unmet clinical need encountered as by clinicians. His research has identified that human perception, dexterity and scale are the limitations of advanced surgical interventions. Image-guided and sensor-enabled intervention technology is capable of overcoming these constraints and Prof Weber’s work seeks to combine simulation and modelling, imaging and sensing, computing, surgical ro-botics and visualization to develop technology that gives “super human” capabilities to clinicians. The challenges of i) localization and targeting of pathological tissue with surgical instruments and focused energy (Hepatobiliary-Oncology) and ii) preci-sion image-guided surgical approaches to microsurgery (Cochlear Implantation) have been resolved successfully by Prof Weber. In addition to his research and translation activities he has founded several success-ful business ventures CAScination AG and LEM Surgical AG to commercialize his research findings. Prof Weber is a Fulbright Laureate, Viterbi School of Engineering, University of Southern California, IEEE member and board member German Society of Computer- and Robot-Assisted Surgery. He has led multi-partner, transnational research pro-grams and is the lead for translational medical technology for the Swiss Federal Government, Canton Bern.

Important Dates of the Bioceramics 33 conference

October 10, 2023

October 11, 2023

October 17-20, 2023

Sponsors Bioceramics 33

Important Dates of the GRIBOI conference

03 September 2023

October 16-17, 2023

Sponsors GRIBOI


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